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1.

A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer.

Takeda, David Y; Spisák, Sándor; Seo, Ji-Heui; Bell, Connor; O'Connor, Edward; Korthauer, Keegan; Ribli, Dezso; Csabai, István; Solymosi, Norbert; Szállási, Zoltán; Stillman, David R; Cejas, Paloma; Qiu, Xintao; Long, Henry W; Tisza, Viktória; Nuzzo, Pier Vitale; Rohanizadegan, Mersedeh; Pomerantz, Mark M; Hahn, William C; Freedman, Matthew L.

Cell ; 174(2): 422-432.e13, 2018 07 12.

Artículo en Inglés | MEDLINE | ID: mdl-29909987

2.

A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.

Subramanian, Aravind; Narayan, Rajiv; Corsello, Steven M; Peck, David D; Natoli, Ted E; Lu, Xiaodong; Gould, Joshua; Davis, John F; Tubelli, Andrew A; Asiedu, Jacob K; Lahr, David L; Hirschman, Jodi E; Liu, Zihan; Donahue, Melanie; Julian, Bina; Khan, Mariya; Wadden, David; Smith, Ian C; Lam, Daniel; Liberzon, Arthur; Toder, Courtney; Bagul, Mukta; Orzechowski, Marek; Enache, Oana M; Piccioni, Federica; Johnson, Sarah A; Lyons, Nicholas J; Berger, Alice H; Shamji, Alykhan F; Brooks, Angela N; Vrcic, Anita; Flynn, Corey; Rosains, Jacqueline; Takeda, David Y; Hu, Roger; Davison, Desiree; Lamb, Justin; Ardlie, Kristin; Hogstrom, Larson; Greenside, Peyton; Gray, Nathanael S; Clemons, Paul A; Silver, Serena; Wu, Xiaoyun; Zhao, Wen-Ning; Read-Button, Willis; Wu, Xiaohua; Haggarty, Stephen J; Ronco, Lucienne V; Boehm, Jesse S.

Cell ; 171(6): 1437-1452.e17, 2017 Nov 30.

Artículo en Inglés | MEDLINE | ID: mdl-29195078

3.

Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis.

Sandoval, Gabriel J; Pulice, John L; Pakula, Hubert; Schenone, Monica; Takeda, David Y; Pop, Marius; Boulay, Gaylor; Williamson, Kaylyn E; McBride, Matthew J; Pan, Joshua; St Pierre, Roodolph; Hartman, Emily; Garraway, Levi A; Carr, Steven A; Rivera, Miguel N; Li, Zhe; Ronco, Lucienne; Hahn, William C; Kadoch, Cigall.

Mol Cell ; 71(4): 554-566.e7, 2018 08 16.

Artículo en Inglés | MEDLINE | ID: mdl-30078722

4.

Implementation of a prostate cancer-specific targeted sequencing panel for credentialing of patient-derived cell lines and genomic characterization of patient samples.

Stover, Elizabeth H; Oh, Coyin; Keskula, Paula; Choudhury, Atish D; Tseng, Yuen-Yi; Adalsteinsson, Viktor A; Lohr, Jens G; Thorner, Aaron R; Ducar, Matthew; Kryukov, Gregory V; Ha, Gavin; Rosenberg, Mara; Freeman, Samuel S; Zhang, Zhenwei; Wu, Xiaoyun; Van Allen, Eliezer M; Takeda, David Y; Loda, Massimo; Wu, Chin-Lee; Taplin, Mary-Ellen; Garraway, Levi A; Boehm, Jesse S; Huang, Franklin W.

Prostate ; 82(5): 584-597, 2022 04.

Artículo en Inglés | MEDLINE | ID: mdl-35084050

5.

Everolimus and pazopanib (E/P) benefit genomically selected patients with metastatic urothelial carcinoma.

Bellmunt, Joaquim; Lalani, Aly-Khan A; Jacobus, Sussana; Wankowicz, Stephanie A; Polacek, Laura; Takeda, David Y; Harshman, Lauren C; Wagle, Nikhil; Moreno, Irene; Lundgren, Kevin; Bossé, Dominick; Van Allen, Eliezer M; Choueiri, Toni K; Rosenberg, Jonathan E.

Br J Cancer ; 119(6): 707-712, 2018 09.

Artículo en Inglés | MEDLINE | ID: mdl-30220708

6.

Association of tumour microRNA profiling with outcomes in patients with advanced urothelial carcinoma receiving first-line platinum-based chemotherapy.

Bellmunt, Joaquim; Zhou, Chensheng Willa; Mullane, Stephanie A; Werner, Lillian; Taplin, Mary-Ellen; Fay, André P; Choueiri, Toni K; Orsola, Anna; Takeda, David Y; Hahn, William C; Kim, Jaegil; Sonpavde, Guru; Bowden, Michaela.

Br J Cancer ; 115(1): 12-9, 2016 06 28.

Artículo en Inglés | MEDLINE | ID: mdl-27351382

7.

Beyond immune checkpoint blockade: new approaches to targeting host-tumor interactions in prostate cancer: report from the 2014 Coffey-Holden prostate cancer academy meeting.

Miyahira, Andrea K; Kissick, Haydn T; Bishop, Jennifer L; Takeda, David Y; Barbieri, Christopher E; Simons, Jonathan W; Pienta, Kenneth J; Soule, Howard R.

Prostate ; 75(4): 337-47, 2015 Mar 01.

Artículo en Inglés | MEDLINE | ID: mdl-25358693

8.

Unpacking circulating tumor DNA lends insight into prostate cancer biology and the clonal dynamics of metastasis.

Takeda, David Y; Sowalsky, Adam G.

Cancer Cell ; 40(10): 1086-1088, 2022 10 10.

Artículo en Inglés | MEDLINE | ID: mdl-36179684

9.

Genetic determinants of chromatin reveal prostate cancer risk mediated by context-dependent gene regulation.

Baca, Sylvan C; Singler, Cassandra; Zacharia, Soumya; Seo, Ji-Heui; Morova, Tunc; Hach, Faraz; Ding, Yi; Schwarz, Tommer; Huang, Chia-Chi Flora; Anderson, Jacob; Fay, André P; Kalita, Cynthia; Groha, Stefan; Pomerantz, Mark M; Wang, Victoria; Linder, Simon; Sweeney, Christopher J; Zwart, Wilbert; Lack, Nathan A; Pasaniuc, Bogdan; Takeda, David Y; Gusev, Alexander; Freedman, Matthew L.

Nat Genet ; 54(9): 1364-1375, 2022 09.

Artículo en Inglés | MEDLINE | ID: mdl-36071171

10.

A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer.

Tang, Stephen; Sethunath, Vidyalakshmi; Metaferia, Nebiyou Y; Nogueira, Marina F; Gallant, Daniel S; Garner, Emma R; Lairson, Lauren A; Penney, Christopher M; Li, Jiao; Gelbard, Maya K; Alaiwi, Sarah Abou; Seo, Ji-Heui; Hwang, Justin H; Strathdee, Craig A; Baca, Sylvan C; AbuHammad, Shatha; Zhang, Xiaoyang; Doench, John G; Hahn, William C; Takeda, David Y; Freedman, Matthew L; Choi, Peter S; Viswanathan, Srinivas R.

Cell Rep ; 38(8): 110417, 2022 02 22.

Artículo en Inglés | MEDLINE | ID: mdl-35196489

11.

Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer.

Baca, Sylvan C; Takeda, David Y; Seo, Ji-Heui; Hwang, Justin; Ku, Sheng Yu; Arafeh, Rand; Arnoff, Taylor; Agarwal, Supreet; Bell, Connor; O'Connor, Edward; Qiu, Xintao; Alaiwi, Sarah Abou; Corona, Rosario I; Fonseca, Marcos A S; Giambartolomei, Claudia; Cejas, Paloma; Lim, Klothilda; He, Monica; Sheahan, Anjali; Nassar, Amin; Berchuck, Jacob E; Brown, Lisha; Nguyen, Holly M; Coleman, Ilsa M; Kaipainen, Arja; De Sarkar, Navonil; Nelson, Peter S; Morrissey, Colm; Korthauer, Keegan; Pomerantz, Mark M; Ellis, Leigh; Pasaniuc, Bogdan; Lawrenson, Kate; Kelly, Kathleen; Zoubeidi, Amina; Hahn, William C; Beltran, Himisha; Long, Henry W; Brown, Myles; Corey, Eva; Freedman, Matthew L.

Nat Commun ; 12(1): 1979, 2021 03 30.

Artículo en Inglés | MEDLINE | ID: mdl-33785741

12.

Prostate cancer reactivates developmental epigenomic programs during metastatic progression.

Pomerantz, Mark M; Qiu, Xintao; Zhu, Yanyun; Takeda, David Y; Pan, Wenting; Baca, Sylvan C; Gusev, Alexander; Korthauer, Keegan D; Severson, Tesa M; Ha, Gavin; Viswanathan, Srinivas R; Seo, Ji-Heui; Nguyen, Holly M; Zhang, Baohui; Pasaniuc, Bogdan; Giambartolomei, Claudia; Alaiwi, Sarah A; Bell, Connor A; O'Connor, Edward P; Chabot, Matthew S; Stillman, David R; Lis, Rosina; Font-Tello, Alba; Li, Lewyn; Cejas, Paloma; Bergman, Andries M; Sanders, Joyce; van der Poel, Henk G; Gayther, Simon A; Lawrenson, Kate; Fonseca, Marcos A S; Reddy, Jessica; Corona, Rosario I; Martovetsky, Gleb; Egan, Brian; Choueiri, Toni; Ellis, Leigh; Garraway, Isla P; Lee, Gwo-Shu Mary; Corey, Eva; Long, Henry W; Zwart, Wilbert; Freedman, Matthew L.

Nat Genet ; 52(8): 790-799, 2020 08.

Artículo en Inglés | MEDLINE | ID: mdl-32690948

13.

Mutational processes shape the landscape of TP53 mutations in human cancer.

Giacomelli, Andrew O; Yang, Xiaoping; Lintner, Robert E; McFarland, James M; Duby, Marc; Kim, Jaegil; Howard, Thomas P; Takeda, David Y; Ly, Seav Huong; Kim, Eejung; Gannon, Hugh S; Hurhula, Brian; Sharpe, Ted; Goodale, Amy; Fritchman, Briana; Steelman, Scott; Vazquez, Francisca; Tsherniak, Aviad; Aguirre, Andrew J; Doench, John G; Piccioni, Federica; Roberts, Charles W M; Meyerson, Matthew; Getz, Gad; Johannessen, Cory M; Root, David E; Hahn, William C.

Nat Genet ; 50(10): 1381-1387, 2018 10.

Artículo en Inglés | MEDLINE | ID: mdl-30224644

14.

DNA replication and progression through S phase.

Takeda, David Y; Dutta, Anindya.

Oncogene ; 24(17): 2827-43, 2005 Apr 18.

Artículo en Inglés | MEDLINE | ID: mdl-15838518

15.

The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis.

Pomerantz, Mark M; Li, Fugen; Takeda, David Y; Lenci, Romina; Chonkar, Apurva; Chabot, Matthew; Cejas, Paloma; Vazquez, Francisca; Cook, Jennifer; Shivdasani, Ramesh A; Bowden, Michaela; Lis, Rosina; Hahn, William C; Kantoff, Philip W; Brown, Myles; Loda, Massimo; Long, Henry W; Freedman, Matthew L.

Nat Genet ; 47(11): 1346-51, 2015 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-26457646

16.

Degradation of Cdt1 during S phase is Skp2-independent and is required for efficient progression of mammalian cells through S phase.

Takeda, David Y; Parvin, Jeffrey D; Dutta, Anindya.

J Biol Chem ; 280(24): 23416-23, 2005 Jun 17.

Artículo en Inglés | MEDLINE | ID: mdl-15855168

17.

Recruitment of ORC or CDC6 to DNA is sufficient to create an artificial origin of replication in mammalian cells.

Takeda, David Y; Shibata, Yoshiyuki; Parvin, Jeffrey D; Dutta, Anindya.

Genes Dev ; 19(23): 2827-36, 2005 Dec 01.

Artículo en Inglés | MEDLINE | ID: mdl-16322558

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